Biocompatible Behavioral Properties of Gelatin/Poly(aniline) Films.

      Аннотация: In this work, glyoxal (Glox) - crosslinked gelatin (Gel) films have been loaded with aniline molecules, followed by their in-situ oxidative polymerization to yield Gel/poly(Ani) composite films. The films, so prepared, have been characterized by FTIR, XRD, TGA and SEM analysis. The water absorption of these films has been studied in the physiological fluid of pH 7.4 at 370C.The dynamic water uptake data has been interpreted by various kinetic models such as power function model and Schott kinetic model. The various diffusion coefficients have also been evaluated. The mechanical/electrical properties of Gelatin/poly(aniline) composite films have been investigated. The moisture uptake behavior of the plain Gel and Gel/poly(Ani) films has been studied under various relative humidity (RH) and at different temperatures. The data obtained has been interpreted in the terms of GAB model. The thermodynamic parameters such as qst and sd have also been determined using Clasius-Clapeyron equation. It was found that both, the qst and the sd decreased with moisture contents. Finally, the films exhibited fair biocompatible behavior.

Ключевые слова: Gelatin, Films, Protein, Cross-linking, swelling