Undifferentiated Mesenchymal Stem Cells of Dental Pulp. Role in repair and regeneration

      Аннотация: The dental pulp is a unique connective tissue which hosts a number of cells capable of undergoing repair and regeneration of the dental tissues. This is possible due to the presence of undifferentiated stem cells residing the core of the detal pulp. The stresses induced on these stem cells along with the restorative materials used for the dental treatment procedures, play an important role in modulation of the stem cells physiologically and functionally. This book offers detailed explanation on how this significantly less used reserve of stem cells may possibly have a key role not only in regenerative endodontics, but also for management of many degenerative diseases in the human body. This book focuses on eradicating the current “Tooth drill and fill” policy by emphasizing on regenerative endodontic procedures and designing biomaterials that replicate the remodelling dynamics of the extra cellular environment of the dental pulp.

Ключевые слова: dental pulp, Stem cells, Repair, regeneration, Caries, inflammation, Biomaterials, cryopreservation, Growth mediators, Cell receptors