Role of Nucleic Acid Testing (NAT) in blood safety. Comparison between NAT and other methods in detection of transfusion transmitted viruses

      Аннотация: The goal of any transfusion service is to provide adequate and safe blood and blood products that meet the needs of patients. Transfusion transmitted infections (TTIS) is a recognized complication of blood transfusion and blood products. Many of these infectious agents may cause lifetime morbidity and/or mortality. The three major TTIs of viral origin associated with blood transfusion are human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV)Nucleic acid testing (NAT) is a molecular technique for screening blood donations to reduce the risk of TTIs in the recipients, thus providing an additional layer of blood safety.

Ключевые слова: transfusion, testing, Nucleic Acid, virus