Coriandrum Sativum L. phenolic extract loaded on copolymer hydrogels. Pharmacological evaluation of phenolic compounds isolated from Iraqi Coriandrum Sativum L. on copolymeric hydrogels

      Аннотация: Medicinal plants are a rich source of compounds that help to fix much of the health tackles. Coriander or Coriandrum Sativum L. is recognized for food and medicine use because it has many bioactive compounds, especially phenol compounds that have antioxidant capacities that help prevent many diseases. Hydrogels are smart and developed soft materials with great applications such as drug delivery. The development of bioapplications of phenol extracts and hydrogels by loading the phenol extracts on hydrogels is interesting and requires more understanding. In this study, the preparation of eight phenol extracts for leaves and stems mixture (L+S) parts and leaves (L) part of Iraqi Coriandrum Sativum L. and their phytochemical analysis and total phenols, total tannins and total flavonoids are described. Three copolymeric hydrogels loaded with phenolic extract 4 of Coriandrum Sativum L. (U1-U3) via redox polymerization were prepared and studied as a drug delivery system. The antioxidant and antibacterial activities of the phenolic extracts and phenolic extract loaded with hydrogels were examined.

Ключевые слова: phenolic compound, Coriandrum Sativum L, coriandrum sativum, copolymeric hydrogels, Iraqi Coriandrum Sativum L