Spheronization, Scale-Up & Coating Ibuprofen with Fluid Bed Technology.

      Аннотация: Rotor disk fluid bed (RDFB) is a one-pot process that saves you time and cost. Traditionally, the development of spherical microparticulates involves extrusion spheronization, a four-step process which is difficult to optimize, reproduce and scale-up. You're about to read about a very powerful technology, which will save you all the time and materials you need to produce affordable food and medications for your patients, consumers and clients. This powerful tool is RDFB technology, a one-step closed spheronization process that utilizes a rotor. The RDFB can also be used for granulation, drying, drug layering and coating. Moreover, the RDFB can be automated to enhance scalability, batch-to-batch reproducibility, reduction of process time and cost. For the brand-name & generic pharmaceutical companies as well as the food industries, the RDFB technology is a genie. By using the RDFB process, the FDA and other regulatory agencies will give you some break because the fluidization of the particles leads to cost-effective product with desirable content uniformity, a parameter that is a sine qua non for the approval of products manufactured for human and animal consumption. Please read on…<div><p>Rotor disk fluid bed (RDFB) is a one-pot process that saves you time and cost. Traditionally, the development of spherical microparticulates involves extrusion spheronization, a four-step process which is difficult to optimize, reproduce and scale-up. You're about to read about a very powerful technology, which will save you all the time and materials you need to produce affordable food and medications for your patients, consumers and clients. This powerful tool is RDFB technology, a one-step closed spheronization process that utilizes a rotor. The RDFB can also be used for granulation, drying, drug layering and coating. Moreover, the RDFB can be automated to enhance scalability, batch-to-batch reproducibility, reduction of process time and cost. For the brand-name & generic pharmaceutical companies as well as the food industries, the RDFB technology is a genie. By using the RDFB process, the FDA and other regulatory agencies will give you some break because the fluidization of the particles leads to cost-effective product with desirable content uniformity, a parameter that is a sine qua non for the approval of products manufactured for human and animal consumption. Please read on…</p></div>

Ключевые слова: Coating, Rotor disk, Fluid-bed, Spheronization, Ibuprofen, Scale-up, Encapsulation, Hard gelatin, Microparticulates, Prolonged release, Granulation, Drug layering