Chemistry and pharmacological Applications of Organoselenium Compounds. Focus on organoselenium compounds

      Аннотация: Organoselenium compounds have the seniority over the inorganic ones in the bioavailability. Its toxicity is less than toxicity of inorganic selenium compounds. Novel synthetic selenium compounds may supply a way to reduce toxicity connected with higher selenium ingestion.During the past decade, various studies has been reported about using of organoselenium as enzyme inhibitors, anti-effective agents, inducers for cytokine, immunomodulator and antioxidant.The importance of organoselenium compounds arise from the predominance of C-Se bonds in compounds with biological and pharmaceutical impact.

Ключевые слова: Selenaheterocycles, Ebselen, Antitumor agents