Nanoparticles As A Local Drug Delivery: Evidence-Based Studies. Enhancing Periodontal Therapy Through Targeted Nanoparticle Applications

      Аннотация: This book investigates the burgeoning field of nanoparticles as a sophisticated strategy for local drug delivery within periodontal therapy. Integrating the latest evidence-based studies provides a comprehensive overview of how nanoparticles are poised to transform conventional treatment paradigms. The discussion extends to the various types of nanoparticles utilized in periodontal therapy, including polymeric nanoparticles, liposomes, metallic nanoparticles, and nanostructured lipid carriers. Each type is explored regarding its specific applications, advantages, and limitations in delivering antimicrobial agents, anti-inflammatory drugs, and growth factors directly to diseased tissues. Furthermore, the book highlights how nanoparticles can improve drug stability, enhance tissue penetration, and provide sustained release of therapeutic agents, thereby ensuring prolonged therapeutic effects at the targeted site. The book also assesses the clinical implications of nanoparticle-based drug delivery systems, drawing on evidence from recent clinical trials. It discusses how these systems can potentially reduce bacterial resistance, and improve overall periodontal health.

Ключевые слова: in vivo Study, local drug delivery, nanotechnology, Nanoparticles, Periodontitis, targeted therapy