HPLC Method Development of Fingolimod. A new RP HPLC method developmental & validation of Fingolimod HCL

      Аннотация: Multiple sclerosis is the most common chronic inflammatory disease of the central nervous system and it is the leading cause of neurological disability in young adults. Fingolimod Hydrochloride is the first oral drug approved by the USFDA for treating multiple sclerosis. Fingolimod is a sphingosine 1-phosphate receptor modulator, which sequesters lymphocytes in lymph nodes, preventing them from contributing to an autoimmune reaction. Till now very few methods are available to determine the drug instrumentally. This book is aiming to address that gap with vivid methodology proper explanation & description. An effort has been made to focus on the way of doing method development & validation according to official agencies (ICH) guidelines in maximum parameter along with all figures & tables. This book is written in lucid manner, so this book is must have for students who are pursuing masters & bachelor degree in pharmacy or Analytical Chemistry or any other courses. Researcher in this field & even company personnel analysing this type of drug will find this book very help full. More over in this book a detail description of RP- HPLC is also included. Wish happy reading to all readers.

Ключевые слова: HPLC, method development, validation, Fingolimod