Floating Drug Delivery System.

      Аннотация: Oral drug delivery system represents one of the frontier areas of controlled drug delivery system. Such a dosage forms having a major advantage of patient compliance. Floating drug delivery system belongs to oral controlled drug delivery system group which are capable of floating in the stomach by bypassing the gastric transit. These dosage forms are also defined as Gastro Retentive drug delivery System or hydrodynamically balanced dosage form or gastric floating drug delivery system, which can float in the contents of the stomach and release the drug in a controlled manner for prolonged period. The release rate will be controlled depending upon the type and concentration of the polymer which swells, leads to diffusion and erosion of the drug. Despite tremendous advancement in drug delivery, oral route of administration has received the more attention and success because the gastrointestinal physiology offers more flexibility in dosage form design than other routes. Hence, research continuously keeps on searching for ways to deliver drugs over an extended period of time, with a well-controlled release profile.

Ключевые слова: disintegration, Dissolution, Floating, capsule